MDG1, a twenty-seven residue peptide, undergoes triggered folding to form an unsymmetrical β-hairpin that self-assembles in response to an increase in solution ionic strength to yield a mechanically rigid, self supporting hydrogel.
Since the Pliocene, Holarctic ecosystems assembled in response to shifting climates (glacial and interglacial stages).
The inflammasome is composed of NOD-like receptors (NLRs) such as Nalp3, NLRC4/IPAF, and Nalp1, and the adaptor ASC (apoptosis-associated speck-like protein containing a CARD), that assemble in response to intracellular presence of danger- or pathogen-associated molecular patterns (DAMPs or PAMPs, respectively) (for review see [2]).
For example, PML nuclear bodies assemble in response to sumoylation (a post translational modification; [ 1]).
We first looked at the behavior of Q-bodies, which assemble in response to heat-stress.
Stress granules, as the name suggests, assemble in response to stress signals to sequester transcriptionally silent mRNA molecules and transcription factors (reviewed in [ 30]).
The NLRP3 inflammasome is assembled in response to a broad range of microbial pathogens and medically relevant substances such as crystalline.
The 3D images suggest that the C1-Pro BiFC structures assembled in response to NALP1, NALP3 or IPAF expression were not hollow compared with those induced by ASC expression.
Different inflammasomes assemble in response to distinct stimuli, for example, the NLRP3 inflammasome forms in response to a plethora of pathogens, including influenza A, Klebsiella pneumoniae and Staphylococcus aureus, in addition to endogenous danger signals such as ATP, uric acid crystals, nigericin and hyaluronan.
