The authors hypothesized that GC-1 plays a primary role in assembling cargo for the IFT particle bound for ciliary delivery.
In polarized cells, it assembles different cargo vesicles that are then transported either to the apical or the basolateral cell surface [115,116].
In yeast, the retromer complex consists of two independently assembled subcomplexes: the cargo selective VPS subcomplex, consisting of Vps35p, Vps26p, and Vps29p and the membrane-binding dimer formed by Vps5p and Vps17p.
In this system, kinesin motors are able to form transient interactions with Qdot cargos, allowing for the study of self-assembled cargos that assemble and disassemble during transport.
When a complex of Slx9, RanGTP, and cargo is assembled, it further recruits Crm1 to the cargo.
The scale of shipments was very large, according to officials familiar with the pipeline and to an arms-trafficking investigator who assembled data on the cargo planes involved.
This past weekend we brought our traveling multi-media extravaganza to Platoon Kunsthalle in South Korea, a futuristic modular structure assembled from 28 recycled cargo containers that functions as the hub for Seoul's underground arts scene.
"We'll have some emergency kits, first-aid kits, a lot of tarpaulins for building shelters," he said as cargo was assembled for the flight late last week.
Similar to other products, trepang flowed through a shifting hierarchy of collecting points where cargoes were assembled.
It also plans to assemble some A330 cargo planes in Mobile, Ala., if it wins a contract to supply the Air Force with refueling tankers based on that aircraft.
