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Such assays may include quantitative reverse transcription PCR, western analysis for total and phospho-proteins, proteomic analysis, flow cytometry or ELISA to demonstrate changes at the RNA or protein levels.
Molecules already known to modulate the activity (e.g. inhibitors or agonists) are sometimes included for comparison; known inactives may be present as internal controls; assays may include several different chemotypes or scaffolds; indeed, the molecules in an assay may bear no structural similarity beyond hitting a particular target (e.g. the result of a HTS campaign).
Furthermore, cohorts of HIV seroconverters who are followed over time to determine the window periods and misclassification rates of HIV incidence assays may include women who either are or become pregnant during the observation periods.
Similar(57)
They may include assays, interventions, or manipulations--whatever techniques you used to collect relevant data.
Other sensors may include handheld assays, vehicles equipped with scoops and laboratory analysis tools, and both point and standoff sensors.
For process validation, operator validation or periodic process control, additional functional tests such as chemotaxis or phagocytosis assays may be included, but this is not required for routine use.
Such methods may include mass spectrometry, enzyme-linked immunosorbent assays (ELISA), and reverse transcription-polymerase chain reaction (RT-PCR).
These may include speedier privatisations.
Side effects may include heartburn.
That may include its architect.
It may include biometric data too.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com