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This is a collection of multiplexed gene expression assays focused on Phase I and II xenobiotic metabolizing enzymes and transporters.
In contrast, the reagents and conditions defined in this study provide a firm foundation for the future development of screening assays focused on changes brought about by protein-protein interactions.
While these assays focused on the embryonic salivary gland, qualitatively similar observations were made in other tubular organs.
Chronic toxicity assays focused on the more common dosage with high probability of occurrence in clinical practice.
The first set of transient expression assays focused on the ability of the piggyBac vectors containing the dual constitutive transcriptional element (ie1-hr5-ie1) to induce heterologous gene expression.
Novel technologies for rapid detection of anti-TB drug resistance have therefore become a priority in TB research and development, and molecular line probe assays focused on rapid detection of RIF resistance (alone or in combination with INH) are now commercially available.
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Microscopic assays focus on only a readily-observed subset of cells within a starved organism, however, and studies rarely attempt to compare the effects of autophagy across multiple tissues in response to nutrient limitation.
Together with other in vitro assays focusing on toxicology and bioavailability, they provide a powerful tool to aid drug development.
Traditionally, biochemical assays focusing on the strand transfer activity of integrase have been used to screen compound libraries for identification of novel inhibitors.
To solve the dilemma between sensitivity and specificity, a new generation of assays focuses on the pathogenic factors that underlie the development of HPV-associated tumors: the expression of the viral oncogenes E6 and E7.
Thus, we decided to further investigate the responses of TTL−/− neurons in response to guidance factors using in vitro assays, focusing on axons pathfinding.
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