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We carefully assayed the development of fibrosis in both transgenic models by use of various methods.
In the present study we assayed the development of primary CD8+ T cell immunity against T. gondii infection in IL-15 deficient mice that are depleted of IL-7.
For confirmation of the dominant loss-of-function mode of action of the dSpt1 C129W mutant SPT subunit, we assayed the development of the larval NMJ.
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As neurotransmitter signalling behaviour cannot be monitored effectively in in vitro assays, the development of in vivo electrochemical biosensors for the understanding of brain is important [61].
41 In fact, co-detection of multiple viruses in respiratory infections has been increasingly frequent as a result of the availability of more accurate detection assays, and the development of microarrays and multiplex detection assays.
The impact of antibodies on sporozoite invasion can be determined in invasion inhibition assays where the development of liver stage parasites after incubation of primary human hepatocyte cultures with P. falciparum sporozoites is quantified.
Moreover, hPSCs and their differentiated derivatives could be applied to chemical compound screening assays for the development of new potential pharmaceuticals and toxic or mutagenic reagents [ 53].
In both assays, the development of a complete embryo is monitored and evaluated during certain embryonic and foetal stages.
In this adapted P. cynomolgi assay, the development of two distinct populations of parasites is monitored in the cultures: small forms that resemble hypnozoites both in appearance and in drug sensitivity profile and developing liver stage schizonts (21).
Through Small Business Innovative Research and Small Business Technology Transfer grants and contracts (NIH 2013b, U.S. EPA 2013c), research collaborations, and communications with commercial assay suppliers, the development of in vitro assays compatible with qHTS requirements has increased.
The flexibility of the Salmonella assay prompted the development of methods to prepare environmental samples for the assay (Hewitt and Marvin 2005; Marvin and Hewitt 2007).
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