Sentence examples for assay with a large from inspiring English sources

A high-throughput assay with a large population of neurons would be useful and efficient to characterize neuronal activity based on the dynamics of synaptic vesicles for the study of mechanisms or to discover drug candidates for neurodegenerative and neurodevelopmental disorders.

Here we report a simple method, termed the BoNT Assay with a Large Immuno-sorbent Surface Area (ALISSA), that uses common laboratory equipment and commercially available reagents.

Here we describe a botulinum neurotoxin serotype A assay with a large immuno-sorbent surface area (BoNT/A ALISSA) that captures a low number of toxin molecules and measures their intrinsic metalloprotease activity with a fluorogenic substrate.

To efficiently screen large numbers of potential antioxidant compounds, it was necessary to develop a simple cell-based oxidative stress assay with a large window of effect.

Recently, the Kalkum group developed an assay with a large immunosorbent surface area (ALISSA) that could concentrate the zinc-dependent metalloprotease protease located in 50 kDa L-chain of BoNT and monitor the conversion of fluorogenic peptide substrates by the intrinsic endopeptidase activity of bead-captured BoNT.

When the agonist response to CGP12177 was examined in more detail in the cAMP assay (with a larger window to examine the response) it can be seen that it too stimulates a response best described by a two-component response at both the tβtrunc and tβ4C-receptors.

In response, the authors of this study conducted their assay with a larger sample size, shown in Fig.  1b, to demonstrate that their original results were replicable.

Further validation of the GeXP assay with a larger number of clinical samples is necessary before this method can be used widely for routine laboratory testing in China.

Droplet manipulation over open surfaces allows one to perform assays with a large degree of control and high throughput, making them appealing for applications in drug screening or (bio analysis.

This is in contrast to the findings at the human β1 and β3-adrenoceptors (where even in assays with a large experimental window, the CGP 12177 response was best described by a one-component concentration response curve).

because of the ultra-rapid online-SPE LC MS MS (tonline-SPE LC MS MS1.8 min) more total30 sanalysisan be analyzed in one hour, rendering time approach ideal for enzyme inhibition assays with a large sample sets.