Sentence examples for assay will be necessary from inspiring English sources

Although this early stage screening allowed identification of neuroprotective compounds, further validation of hits from this assay will be necessary in higher vertebrate models of ALS.

Moreover, in planta assays will be necessary to validate these yeast-based interactors.

We propose that, in addition to immunolabeling, combination of western blotting and laminin binding assays will be necessary for further advances in both clinical and basic biomedical research.

We do not believe the choice of assay caused the lack of association with mortality in our study, but it cannot be excluded, and direct comparisons of different FGF23 assays will be necessary in the future.

Differences found in mRNA decay according to CD154 genotypes suggest that this polymorphism may contribute to the regulation of mRNA expression, although further assays will be necessary to elucidate its role in disease predisposition.

Thus, while the simpler assays are ideal for rapidly identifying ethanol-related genes and have some predictive value for more complex behaviors, the development of high-throughput versions of the more complex assays will be necessary in order to apply the power of Drosophila genetics to the study of addiction-like behaviors.

An important challenge to be addressed in future experiments is the identification of the substrates of these, and perhaps other, E3 ligases in chloroplasts; this will not be trivial, as it cannot be done in silico, and so multiple experimental assays will be necessary to identify their functions.

Further comparative genomic studies and functional assays will be necessary to determine if Kr-h1's function truly diverges between social and nonsocial Hymenoptera, and between different insect orders, or if the sequence differences are simply due to the accumulation of mutations during evolution in different lineages.

In order to make it a truly quantitative assay it will be necessary either to have a defined start sample regarding species composition or only to use specific primers on the array where high efficiency has been proven.

The digestion of the PCR products with the restriction enzyme BstEII allowed the easy discrimination between "a" and "b" subtypes The diagnostic system based on PCR products has been tested on seventeen isolates and references strains, however before considering the general applicability of this assay it will be necessary to analyze more samples of all BoHV-5 subtypes.

It is clear that massively parallel reporter assays (discussed above) will be necessary to help distinguish functional variants from those that are passengers.