Sentence examples for assay the functionality from inspiring English sources
Because of the low efficacy of chondrocyte transfection with a PPRE-luciferase construct as a gene reporter assay, the functionality of PPARγ ligands was controlled by measuring changes in adiponectin expression.
Thus, in spite of the incompleteness of the spruce genome sequence used to estimate the appropriateness of candidate SNPs for the GoldenGate assay, the functionality score was still a valuable predictor of the likelihood of success of the designed oligonucleotides.
Because silencing c-Cbl increased the abundance and stability of r∆F508-CFTR band C we assayed the functionality of the rescued fraction, predicting that it would also increase the r∆F508-CFTR mediated Cl- secretion.
In our study, suppression assays confirmed the functionality of Treg in rejecting recipient which was similar to Treg of tolerant mice.
Reporter assays showed the functionality of the new binding sites observed in sporadic cases (Huang et al, 2013).
A more detailed investigation of the role of the p53-binding site in the promoters of SEI1, as a representative of a p53-induced gene, and AURKA, representing a p53-repressed gene, using luciferase reporter assay confirmed the functionality of p53 RE in these genes.
Usually, two serological methods are used to estimate the protective antibody levels: standard ELISA measuring antibody concentrations and opsonophagocytic assays measuring the functionality of the antibodies.
Other technologies like cell-based assays, biacore, and homogeneous mobility shift assays can characterize the functionality of anti-drug antibodies; however, the question arises whether characterization of the antibody binding activity is required, when this can be easily answered with a simple ELISA test due to the fact that the immune response detected by ELISA is neutralizing.
We next used in vitro human-mouse blastocyst chimera assay to assess the functionality of iNANOG cells (Fig. 6A).
We then used the melan-d1 complementation assay to test the functionality of these mutants.
In addition, we used this assay to dissect the functionality of the highly conserved Ets/Ets/Gata motif in the Scl+19 enhancer, which revealed that the Gata motif is not required for initiation of enhancer activity.
