Sentence examples for assay setups from inspiring English sources

The influence of consistency of assay setups can directly be quantified via the variability and practical consequences for MMP analysis will be presented.

Here we quantify the effect of several cAMP analogs applying three different biochemical/biophysical assay setups and one in-cell assay.

The different cost levels can be thought of as representations of different assay setups, where for example a more complex phenotypic assay is more costly per compound screened compared to a biochemical assay on isolated protein [27, 28].

In some cases, however, the activity was on the border of the 10 µM cutoff set for separating active from inactive (12 µM for compound ChEMBL73930 and 19 µM for compound ChEMBL258456), and could also point to incoherencies between different assay setups, for example.

Although less intense, more stable staining was characteristic for X-2 staining experiments, where the same intensity of fluorescent signal was retained for at least 72 hours giving this module an important advantage as a specific binding probe in assay setups that demand higher labelling stability.

Cytotoxicity measurements were conducted at E4rGel concentrations between 3 × 10 9 and 3 × 10 8 M and particle concentrations between 12.5 and 37.5 μg/mL (particle concentration was reduced accordingly due to the lowered cell density when particle treatment was initiated compared to the earlier assay setups with a shorter time period before readout).

An inactive compound, although indicates a negative outcome under the examined assay setup, may relate to another phenotype of interaction with the biological target.

Furthermore, during import, datasets are scanned for problematic molecules or features of molecules like Pan Assay Interference Compounds (PAINS), which may disturb the assay setup or unspecifically bind to diverse proteins [26].

TAC technology allows users to spot customized assays and design TAC layout, simplify assay setup, conserve specimen, dramatically reduce contamination potential, and as demonstrated in this study, analyze multiple samples in parallel with good reproducibility between instruments and operators.

In addition to the protocols for assay setup and inoculation onto agar, which were similar to the planktonic assay, the analysis of biofilm activity using the XTT metabolic assay also involved multiple pipetting steps, media exchanges and timed delays that were amenable to automation.

Just prior to analysis, frozen sera were thawed and maintained on ice throughout the assay setup.