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To ensure the reliability of the bioactivity values, only IC50 values corresponding to small molecules and satisfying the following criteria were kept: (i) activity relationship equal to ' =', (ii) assay score confidence ≥ 8, and (iii) activity unit equal to 'nM'.
Only the data satisfying the following criteria was kept: (1) assay score confidence higher than 8, (2) activity relationship equal to '=', (3) activity type equal to "IC50", and (4) activity unit equal to 'nM'.
The measures of AP sites were obtained by subtraction of the mean comet assay score with enzyme buffer alone from that with ExoIII.
The minimum number of tag-SNPs were then selected among all identified SNP using Haploview Barrettt et al, 2005) based on the following criteria: r>0.8 and Illumina assay score >0.60.
The polarization values (mP) of each well were normalized against the assay window using the mean polarization values of the no protein control (µ 2 ) and no compound control (µ 1 ) wells to generate an assay score (Equation 4).
A limitation of the concordance analysis is that a few of the Stage I patients may have met guideline criteria for chemotherapy (Her2 neu positive tumor larger than 1 centimeter, triple negative tumor larger than 1 centimeter, or high 21-gene assay score) [ 1, 2].
Similar(54)
As expected, cpr5-1 mutants were also hypersensitive to tea polyphenols (another inhibitor of the LOX pathway) observed in germination assay scored by radicle emergence as well as in assays measuring the emergence of green cotyledons (Figure 9).
This assay scores for trimethoprim (Trim) resistance due to the regeneration of functional murine dihydrofolate reductase (mDHFR) activity from two independent mDHFR protein fragment domains fused to two potential protein interaction partners.
For automated image acquisition and MN scoring, a Pathfinder™ Cellscan μN platform for automated micronucleus assay scoring (IMSTAR) was used.
Chemoresponse assay scores for the seven single-agent therapies were further evaluated using two-dimensional clustering analysis.
Individual Biolog PM assay scores for each well were compared across experimental datasets to establish a consensus for comparison with EcoCyc 18.0 GEM simulation.
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