The phrase "assay paradigm" is correct and usable in written English.
It can be used in contexts related to scientific research, particularly in discussing methods or frameworks for analyzing substances or data.
Example: "The new assay paradigm introduced in the study significantly improved the accuracy of the results."
Alternatives: "testing framework" or "analysis model".
In an effort to design an assay paradigm for the development of JAK2 selective inhibitors, we investigated whether compound selectivity differed between cellular and purified enzyme environments.
In the existing clinical assay paradigm, only hotspot mutations (such as those discussed earlier in the EGFR tyrosine kinase domain) are sequenced from tumor tissue only.
Hence, the comparator normal sequence is critically important to define precisely which variants are somatic, but including the normal tissue doubles the cost of sequencing and disrupts the existing clinical assay paradigm.
We hypothesized that the concurrent genomic landscape of these tumors, which is currently unknown in view of the prevailing single gene assay diagnostic paradigm in clinical practice, could play a role in clinical outcomes and/or mechanisms of resistance.
According to the measurement paradigm, assays claiming the same measurand should give equivalent results within clinically relevant constraints.
This article presents some considerations for navigating the world of quantitative laboratory-developed assays and proposes a paradigm for developing a quality system for these assays.
The Salmonella assay led to two paradigm shifts: that some carcinogens were mutagens and that some environmental samples (e.g., air, water, soil, food, combustion emissions) were mutagenic.
Given the much broader range of biology that future assays will detect, new paradigm shifts will emerge in other areas of toxicology from 21st century assays.
Taken together, these data demonstrate the potential for two complementary imaging paradigms that assay dynamic changes in TSPO levels in vivo.
We employed two different paradigms to assay visual learning in walking flies.
As the field advanced beyond HDACs toward the discovery of histone methyltransferase (HMT) inhibitors, it became clear that each class of enzymes would require new assays and screening paradigms.
