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Large cohort studies are necessary for defining the usefulness of each assay, in terms of specificity, sensitivity, accuracy and for following-up the disease evolution.
The accuracy of the assay, in terms of specificity, was 100%, as none of the NTM strains tested revealed any amplification product.
The proposed enzymatic detection method was detailed and compared with the conventional guanine oxidation based assay in terms of detection limit and specificity.
However, in the 24-h FDA assay, in terms of the number of particles per well and the resultant total surface area per well, the 50 nm IO nanoparticles are more toxic than those of size 10 nm.
Hovering over the Assay Name lists the details of a particular assay in terms of organism, tissue type, measurement technology and other details (see Fig. 8).
The proliferation of HNEpC on the Ti specimens was examined using the MTT assay, in terms of cell viability, at 2, 4, and 6 days, as illustrated in Figure 7.
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Compounds 6a c are potent free radical scavengers as demonstrated by the EC50 values in PC12 cell survival assay in term of NO, H2O2, and OH scavenging activity.
Digital PCR (dPCR) assays have an advantage over real-time quantitative PCR assays in terms of sensitivity and precision.
Recommendations for optimisation of in vivo assays, in terms of the 3Rs philosophy, applied to performing tests, harvesting data and appropriate reporting are summarised as a checklist of issues to be addressed prior to undertaking such assays.
The specific target receptor interactions on the cantilever surface can be assayed in terms of either cantilever deflection or change in resonant frequency.
Overall, these results provided strong corroboration of the gene chip assays, in terms of both the identification of differentially expressed genes and the magnitude of the differential expression.
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