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In the case of prostate cancer patients, the results were similar, with the STK1 protein assay improving sensitivity 3-fold compared with the activity assay.
Further standardising the membrane feeding assay, improving the accuracy of QT-NASBA technique and the inclusion of additional covariates (such as estimates of gametocyte maturity which have been investigated in P. vivax (Chansamut et al., 2012)) would improve the accuracy of the relationship between gametocyte density and mosquito infectivity.
These questions fall into three main groups: 1) those related to gaining a better understanding of the assay, improving its performance and investigating optimum sample storage; 2) those assessing diagnostic accuracy and issues surrounding implementation, and 3) those assessing impact and cost.
Further standardising the membrane feeding assay, improving the accuracy of QT-NASBA technique and the inclusion of additional covariates (such as estimates of gametocyte maturity, which have been investigated in Plasmodium vivax; Chansamut et al., 2012), would improve the accuracy of the relationship between gametocyte density and mosquito infection.
Further standardising the membrane feeding assay, improving the accuracy of QT-NASBA technique and the inclusion of additional covariates (such as estimates of gametocyte maturity which have been investigated in P. vivax (Chansamut et al., 2012)) would improve the accuracy of relationship between gametocyte density and mosquito infectivity".
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Further improvement of the assay improved the detection limit to 1,000 cells/ml.
Furthermore, this P. aeruginosa protease assay improves upon existing assays because it is simple, it requires only one step, and even more significantly it is enzyme specific.
Adding NCp7 to the assay improved the 99 nt-long strand displacement synthesis required at the end of the reaction to generate the HIV-1 central DNA flap [30].
The assay improved the detection of dengue when used in combination with serological methods.
Mitotic recovery was subsequently enhanced and tissue regeneration as measured by the crypt survival assay improved (Bach et al, 2000).
Introduction of the α-fetoprotein biochemical assay improved sensitivity, but it was still poorly reliable by current standards.
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