Sentence examples for assay domain from inspiring English sources

CLIA instruments steadily infiltrated the immunometric assay domain, eventually being used to measure serum concentrations of hormones, drugs, vitamins, tumour markers, infectious disease markers, myocardial damage markers and, finally, autoantibodies.

Based on standard ADA screening and confirmation assays, respectively, domain detection assays (DDAs) and domain competition assays (DCAs) were established and compared by the use of 12 ADA-positive samples obtained from a cynomolgus monkey study in early development.

Next, we assayed the domain contribution of SR proteins in mediating β-catenin accumulation.

In vitro binding assays and domain mapping experiments revealed the existence of a previously unknown RBR within SCML2.

Using deletion mutants and pull-down assays, the domain for interaction with RPA70 has been shown to reside between residues 153 to 176 of human XPA [ 6].

In agreement with this, we reported a significant correlation between immunohistochemical data and [H]oestradiol-binding capacities measured by hydroxylapatite assay; ABC domains are indeed required for hydroxylapatite adsorption [ 12].

At the end of incubation, tubes were transferred to the ice and subsequently washed (3×) to remove reaction mixture and finally resuspended in 50 mM Tris-Cl buffer pH 7.4 for subsequent use in an in vitro kinase assay using catalytic domain of insulin receptor and ATP.

Cell lysates were then assessed for Rac activity using a Pak1 Rac Binding Domain assay, as we have performed previously [ 21, 23].

A tempting application of this method would be a multiplex modular domain assay targeting multiple PTMs on receptor tyrosine kinases such as EGFR or PDGFR.

We found that in this assay the PH domain interacted equally well with PI 3,4 P2 and PI 4,5 P2 and exhibited less binding to PI 3,4,5 P2.

In this assay, the Kelch domain of Keap1 is allowed to flow in solution over an SPR sensor chip with the 16mer Nrf2 peptide immobilized on the sensor chip surface.