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If Gallup polled high-school students, it would need a category called "Why are you even asking?" The accumulation of state laws that extend marriage rights to gay couples is slow but steady.
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We asked whether the accumulation of ROS in the cln3 mutant flies was due to a failure to upregulate antioxidant gene transcription in response to oxidants.
To ask whether the accumulation of oxidatively damaged proteins is increased in the sir2Δ mutants, we performed the carbonyl assay to detect the overall level of oxidatively damaged proteins.
Since vHMEC expressing oncogenic ras exhibited many characteristics observed during the progression to malignancy, including increased genomic instability, upregulation of telomerase activity, and unlimited proliferative capacity, we then asked if the accumulation of these molecular alterations had rendered these cells tumorigenic.
A number of economic observers have asked the question: Are countries heading back to the bad old days of rapid debt accumulation that may need to be forgiven down the line?
Joe Askew asks the questions.
Nobody asked the patient.
The C. elegans gonad thus provides a highly suitable model system to ask how organs minimize the accumulation of mutations, and what role stem cells play in that minimization.
Thus, we asked whether deltaFosB accumulation in the MS/vDB, which constitutes the major cholinergic projection to the hippocampal formation, cingulate cortex and the hypothalamus [ 29] could be influencing cholinergic signaling.
One may ask whether the different accumulation profile shapes we observed for YB1 and PRC1 correspond to their biological function.
In the reciprocal assay, we asked whether mutations in Rhi abolish the accumulation pattern of Cuff.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com