Aside from the predominant expression profile of H19 (1st split, H19 is not represented on the human array), the remaining genes split into 2 clusters (2nd split).
Aside from the constitutive expression of CD25, TR cells show elevated levels of adhesion molecules such as CD11a (LFA-1), CD44, CD54 (ICAM-1), CD103 (αEβ7 integrin) in the absence of any apparent exogenous antigenic stimulation [ 14, 15].
Aside from these expression data, a role of ID4 as a putative tumour suppressor in human breast cancer development has been discussed controversially and is uncertain yet.
In females, aside from the halteres, Gal4 expression was only detected in the posterior midgut both before and after blood feeding.
Aside from elevated expression in the lens placode and pigment epithelium, cochlear epithelium, and condensing mesenchyme at sites of myogenic or cartilage formation, there is little focal expression at fetal stages (see Fig 4L N; E12.5 and E14.5 are shown).
Of course, aside from divergent expression of orthologous genes, a feature of the evolution of the immune system across species, and even within species, is the gain and loss of individual genes, especially within gene families [ 9].
As different human genes undergo various selective pressures in association with their expression patterns [ 33], we wonder whether expression pattern, aside from expression level, plays a role in shaping heterogeneity of translational selection acting on human genes.
4ebp mRNA, a transcriptional target of dFOXO, is elevated in tissues aside from the site of dilp6 over-expression, suggesting that over-expression of fat body dilp6 systemically reduced insulin/IGF signaling.
Nowadays, it is well established that this protein can be expressed by different cell types, aside from its expression in Tregs, which include normal [21] and tumor [20, 43] cells.
Therefore, aside from gene expression profiling, immunohistochemical detection of MCM6 seems to be the most promising marker for predicting the outcome in MCL.
