Exact(1)
Although simple sequence analysis of regulatory regions from diverse and related members of a species can readily ascertain whether sequence variation is present and heritable, ascertainment of impact on gene expression from sequence alone is less precise.
Similar(59)
We compare the finding of these 2 methods of case ascertainment and the impact of different case definitions on surveillance data from 2000 to 2007.
14 The original study (commissioned by NHS R&D) was tasked with assessing alternate methods of case ascertainment and their impact on assessment of quality of care.
With a comprehensive list of all published variants analyzed using IT-based methodSupplementaryary Bibliography), we perform a meta-analysis of all of these variants to minimize bias in interpretation and impact of ascertainment of specific phenotypes from individual studies.
Although such studies are susceptible to confounding and to bias due to differential ascertainment of cases, investigators can mitigate the impact of these biases by standardizing measures of key variables, achieving near complete case ascertainment, and evaluating the representativeness of the included cases.
Further epidemiologic studies will need to address whether the apparent emergence of melioidosis in northeastern Brazil is due primarily to improved ascertainment, the regional impact of climate change, changes in land use, or a combination of these factors.
Evidence of Impact.
Area of impact.
The methods for case ascertainment significantly impact incidence estimates.
Thus, extending the window for ascertainment of colonoscopy is unlikely to have a substantive impact on the findings.
The mode of ascertainment of diabetes, self-report versus objective measurement, did impact the risk relation with volume of alcohol exposure but only for men; there was no effect for women.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com