Biologic markers are often used to ascertain validity of reported data (38 ).
Key interpretations were checked by participants to ascertain validity at the end of each discussion or interview.
Nevertheless, further research is needed to ascertain validity across institutions, languages (present results stem from the German version of the questionnaire) and cultural contexts.
To ascertain validity, we assessed all selected trials for their methodological quality on the basis of information reported in the original published papers, trial protocols (for non-published trials), and responses to specific queries to the authors.
Several studies examined different facets of validity, ascertaining both concurrent validity —sensitivities of 69%to100%00 %, specificities of 65%to94%94 %, and areas under the Receiver Operating Curve (AUROC) varying from 0.77 to 0.91 [ 17– 21]— and construct validity —correlations between the IQCODE and cognitive screening tests and neuropsychological tests ranging from −0.12 to −0.78 [ 17, 22].
Ascertaining the validity of this interpretation would require following youth with type 1 diabetes as they age into adulthood to determine change in rate of insulin omission.
Ascertaining the validity of this interpretation would require following adults with type 2 diabetes as they age to determine change in rate of insulin omission.
However, impairment criteria are not only relevant in ascertaining the validity of caseness; they also have the potential to identify children and adolescents who are not detected when only symptom-related diagnostic criteria are applied [ 2, 10, 20].
Ascertaining the validity of a carefully crafted fake autograph is a complex matter which is almost impossible for the amateur and the results cannot always be definitive even when a professional opinion is requested.
The patient-directed data collected here were not the focus of this feasibility study and were not analyzed to ascertain the validity of BrainCheck (see Validation study).
