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The condition of this corpse was, as far as I could ascertain, the same as that of all the other corpses.
Therefore, there is a need to ascertain the same information using a small number of markers.
Cases ascertained in the UK in travelers were obtained from a comprehensive scan of press reports cross-checked with UK Health Protection Agency daily updates to ensure consistency of numbers, and possible clusters were ascertained the same way.
It was therefore not easy to ascertain the same level of data quality across the study countries.
In a limited number of cases, we also evaluated the effect of SNP ascertainment bias when SNPs were selected in a population different from the target population, as opposed to ascertaining the SNPs in the same population.
These two variants (V1 and V2, Table 1) were present in trans to known disease-causing ABCA4 mutations, are predicted to increase the strength of the splice signal in which they occur (Table 2) (8), were not present among 600 control alleles ascertained in the same clinic population, and were not present among 2184 alleles in the 1000 genomes database (9).
Prospective studies represent a more controlled setting where both case and control subjects are ascertained in the same way and have similar environmental exposure and therefore give the true incidence of the disease in a population.
In order to assess the benefits of transethnic GWAS for the detection and fine-mapping of novel loci for complex traits, I have repeated simulations of the transethnic fixed-effect model under two scenarios: (i) 11 GWAS of 1,000 individuals, each ascertained from a different HMP3 population; and (ii) 11 GWAS of 1,000 individuals, each ascertained from the same CEU population.
The PFGE profiles from S. aureus identified from mothers (nasal, nipples, milk and vagina) will be compared to isolates cultured from her infant's mouth to ascertain whether the same strain of the organism is present and to determine transmission dynamics.
It is often difficult to ascertain whether the same composer created both the words and the music in a folk song; many songs are known to have separate sources for words and music.
The objective is to ascertain whether the same methodologies can be considered for coking coal, which could lead to elimination of present day bottlenecks that occur with bulk solids hauling.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com