Curnow et al were not able to accurately ascertain in which tissue layer the polarographic Eppendorf needle is located during measurements.
Hence, although C11-BODIPY581/591 may be used as a probe to monitor lipid peroxidation, we cannot readily ascertain in which cellular compartment this lipid peroxidation is occurring, nor in which compartment or membrane(s) MGST1 is exerting its protective effect.
Although several of them may be pseudogenes, genes inactivated by the accumulation of deleterious mutations, it may be quite difficult to ascertain in which tissues, if any, these genes are expressed if they share a high percentage of homology.
Capturing of cell and tissue type information alongside subcellular localization and protein molecular function can enable users to quickly ascertain in which cells or tissues certain peroxisomal-based functions are performed.
This is of course just normal pedestrian evolutionary biology, and, as Glansdorff et al. clearly state, Darwinian thinking (i.e. not presuming, a priori, to know the ancestral state, and, accepting, that we cannot, a priori, ascertain in which lineages we might find the ancestral state, if at all) is preferable to applying Lamarckian notions of 'progress'progress
For example, if a colored block comprising 3 squares totals 7, then the individual squares must be 1, 2 and 4, but it is down to the reader to ascertain in which order they must be placed.
By ascertaining ways in which perceived stressors associated with this transition are experienced, we can inform design and delivery of services and supports to circumvent or alleviate such burdens or stressors.
Forty three people with diabetes were purposively recruited to ascertain ways in which they managed their disease in the workplace.
By auditing against best practice, aged care services can ascertain areas in which they need to improve and develop and implement strategies to do so.
Second, we used rejection sampling to simulate an ascertained sample in which at least one sibling was affected (D S is always affected).
Although HyperGen, like Genetic Epidemiology Network of Arteriopathy (GENOA), ascertained sibships in which 2 or more siblings had essential hypertension diagnosed before age 60, the HyperGen linkage analysis was conducted after pooling the black and white cohorts.
