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Informed consent procedures and protocols for examinations were approved by the Joslin institutional review board, as were methods for ascertaining dates of onset of ESRD and death.
Though it would be interesting to assess survival from disease onset and the potential impact of delay until diagnosis, we were unable to do so because of the difficulty in reliably ascertaining dates of IIM onset.
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In the original study, we excluded individuals reporting irritable bowel syndrome (cases = 221, 9.3%; controls = 324, 6.2%), because of difficulties ascertaining date of onset and because risk factors in this group may differ.
The other bridal gown, Mrs. Lowry ascertained, dates from the 1870's.
We used diagnostic codes to ascertain dates of first-incident hospital admissions for cardiovascular diseases, respiratory diseases, and fractures.
The school calendar was used to ascertain dates that would have high absenteeism because of teacher planning days, early release days, holidays, and other events.
All schizophrenia-spectrum cases were also searched for on the Victorian Registry of Births, Deaths and Marriages to ascertain dates of death where applicable.
For each outcome we selected the patients within the study cohort with the outcome of interest during the study period and ascertained dates when they started and finished taking statins.
The inability to ascertain dates of risky behaviors and HIV seroconvertion made it impossible to assess HIV transmission dynamics in this study, and provides a rationale for future longitudinal studies.
To ascertain dates of diagnosis of prostate cancer incidence and prostate cancer as a cause of deaths in these three cohorts, we linked the background register to the CER 60/70 proper, matching on all variables that both these datasets had in common.
The Medical Informatics database was also queried to ascertain date of death.
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