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Although EDC proponents frequently claim that clinical trial data quality improves with use of such systems, studies supporting this contention have yet to appear in the peer-reviewed literature, and it is not clear whether traditional methods of ascertaining data quality suffice for EDC trials.
There were significant geographic challenges in locating and ascertaining data from the subjects in childhood.
Finally, evidence was rated as 'insufficient' if a paper had an unclear or inappropriate method of ascertaining data and insufficient analysis.
After ascertaining data compliance to normality, we used the pairwise t-test for the comparison of the aluminum concentration in the central, peripheral and normal areas of the tumors.
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Using medically ascertained data, we applied the cumulative burden metric to compare chronic cardiovascular health conditions in survivors of Hodgkin's lymphoma and general population controls.
To ascertain data quality, we employed two supervised classification analyses: linear discrimination analysis (LDA) and K-nearest neighbor classification (KNN).
As can be noted visually, very accurate estimates of the unascertained allele frequency distribution are recovered from the divergence ascertained data.
The percent of alleles captured by these core sets was only slightly lower than was found for the ascertained data (Table 5), suggesting that we may not have missed a large number of rare SNP alleles.
The 'Boot2 SEs' are computed by bootstrapping the ascertained data.
We ascertained data on HPV vaccinations any time up to and including the study end date.
We ascertained data regarding the incidence of CRC and CRC deaths from these 2 databases.
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