Sentence examples for ascertaining candidate from inspiring English sources

In contrast, here we show that first ascertaining candidate co-adapted genes from population genomic data followed up by an association study is a feasible way to simultaneously detect multiple susceptibility genes for complex (disease) phenotypes even if these lack any individual effect on their own.

This study also shows the limitations with using publicly available SNP data to ascertain candidate QTL genes.

Pool sequencing is a relatively young variant of whole genome sequencing, and it is a challenge to ascertain candidate SNP assays for individual genotyping, which may limit the efficiency of replicating pooled sequence loci using individual genotyping [ 42].

However, the aim of the present approach is rather to first ascertain candidate "co-adapted" genes to be tested for association with complex traits, thus strongly reducing the number of tests in the analysis of specific phenotypes.

This process, which operates by popular vote and employs administrative and judicial processes when needed to ascertain which candidate has prevailed, is the only provision by which the Florida Legislature has established the manner of appointing Florida's presidential electors in the 2000 general election.

To date, most reported disease associations to these variants have been ascertained through candidate gene studies.

To date, most reported disease-to-mCNV associations have been ascertained through candidate gene studies.

Of course, only real-time PCR or CGH analyses would help to ascertain valid candidate genes.

A comprehensive search of the 1.2 Mb genomic region spanning the flavanol QTL cluster on LG 16 was performed to ascertain whether candidate genes other than LAR1 are also located within this QTL interval.

Complex trait phenotyping can be fruitfully combined with genetical genomic analysis to ascertain the candidate genes and gene product interaction pathways which significantly influence the variation in expression of a phenotype of interest.

The biomarker candidates detected in plasma were then subjected to clinical evaluation in two independent cohorts of samples (n = 469) to ascertain biomarker candidates with diagnostic value (Table 1).