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Sequencing e.g. by Next Generation Sequencing methods is likely to play a significant role in ascertaining a genetic diagnosis for these patients in an affordable and timely manner.
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To ascertain a molecular genetic diagnosis for subjects with neonatal/infantile intrahepatic cholestasis (NIIC) by the use of next-generation sequencing (NGS) and to perform a genotype-phenotype correlation.
To ensure the two-study cohort had power to ascertain association, a genetic power calculation was performed using the sample size in the SLE GWAS European American case control cohort and UK|CC data.
Finding links between phenotypical and genotypical changes is of great importance in order to ascertain a better understanding of genetic adaptation and presents the opportunity to improve breeding work through directed selection on favourable genotypes.
The parameters of the controller are ascertained by using a genetic algorithm.
Unlike the minP test which ascertains significance of a genetic region with NHL risk based on the minimum p value after adjusting for the total number of SNPs evaluated in the region, this second method was used to determine if additional genetic regions might be implicated in NHL risk despite no apparent significant SNP association.
A second line of response is to argue that norms of reaction are almost impossible to generate for complex human traits and, as a result, are not a serious contender in the business of ascertaining the genetic causes of human traits.
This may be valuable in ascertaining the genetic contribution to its water use efficiency and possible use in engineering higher water use efficiency in C3 plants.
Ascertaining the genetic background of EC patients can help clarify the molecular genetic mechanisms of esophageal carcinogenesis, improve the evaluation of risk factors in individuals from high-risk populations, and promote the implementation of effective screening and preventive measures.
A subset of 20 randomly selected polymorphic EST-SSRs producing one or two amplicons per genotype was tested for their potential in genetic studies by ascertaining the genetic diversity in panel 2. Alleles were resolved by semi-automated fluorescence-based genotyping to attain a more accurate estimation of the allelic diversity and size range.
The Grandmothers asked him about the scientific feasibility of ascertaining genetic connectedness without the physical presence of a direct relative (i.e., a biological mother or father).
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