The phrase "ascertained variant" is correct and usable in written English.
It can be used in contexts where you want to refer to a variant that has been determined or established through investigation or analysis.
Example: "After thorough research, we identified the ascertained variant of the virus that is currently circulating."
Alternatives: "determined variant" or "established variant."
Although all these approaches can provide high genome coverage and ascertain variants in genes, it is not clear to which extent these approaches could capture the common genic variants.
Additionally, they provide the two ingredients necessary for mapping gene expression traits to genotype, at moderate cost and without the requirement for previously ascertained genetic variants.
With our new approach, we were able to ascertain the variant rate across the entire E2 sequence containing these epitopes, detecting variants in extreme low rates.
Mating preferences of females for males of their own color variant (ascertained in a previous experiment) were not overturned when males of another color variant were presented in a superior territory, indicating that within- and between-population mate preferences of females depend on different cues.
However, the much smaller number of variants ascertained reduces the mapping effectiveness of the approach; that is, when a region with a large number of homozygous variants or a high novel allele frequency is found using the WGS approach, one has considerable confidence that the mutation is resident in that region.
We ascertained ENU-induced variants in four different phenotypically mutant lines.
The remaining reads were then aligned to a final reference sequence and the SNP variants ascertained using SAMtools/bcf.
After excluding all loci previously reported to be associated with human height, we ascertained 12 genetic variants with P < 5 × 10−6 (Fig. 2 and Supplementary Material, Table S2) for further analysis.
We also explored the utility of WES for this purpose, recognizing that, given exome hybridization methods generally capture ~1%% of the genome, the number of variants ascertained could preclude reliable genetic mapping.
Because variants were ascertained by sequencing, the frequency with which the variants were detected in the pooled alleles cannot serve as a reference for statistical comparison.
