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Outcomes measured at the level of families and children's centres will be ascertained using a range of tools delivered as summarised in Table 1 and described below.
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The urinary and plasma biomarker performance was ascertained using a receiver operating characteristic (ROC) curve analysis.
β2AR expression was ascertained using a highly quantitative 125I-cyanopindolol (125I-CYP) radioligand binding assay.
Disease history was ascertained using a questionnaire.
Renal function was ascertained using a combination of indicators.
Dietary intake was ascertained using a modified version of the Kids Food Questionnaire (16).
Diabetes status, as well as all predictor variables, was ascertained using a self-report method [ 26].
The specificity of this signal was ascertained using a control serum for ChIP.
The assumption of heterogeneity was ascertained using a chi-based Q-test.
This will be ascertained using a simple question within the follow-up measure.
The main weakness is that dependency was ascertained using a semi-structured interview.
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