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We further ascertained the functional role of JMJD2B in the pathogenesis of hepatic steatosis in vivo.
In this study, we have employed skeletal muscle-specific gene disruption approach in animal models and ascertained the functional role and isoform-specificity of the p38 MAPK pathway in endurance exercise-induced skeletal muscle adaptation.
Moreover, the analysis of one-leg-hop and one-leg-rising clinical tests results ascertained the functional efficiency of operated knee.
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In order to try and ascertain the functional role of RasGrf1 in pancreatic islet and beta cell function, here we used commercial microarrays to characterize the specific transcriptional profile caused by the disappearance of RasGrf1 from the pancreatic islets of our RasGrf1 KO mice.
And though much more research is needed to ascertain the functional consequences of these brain changes, in some tests, heavy users demonstrated a reduced ability to solve complex problems on intelligence tests and showed signs of short-term memory loss.
To ascertain the functional role of stress-induced CRF release onto LDTg cholinergic neurons, and the respective contribution of CRF-1 or CRF-2 receptor subtypes, we performed whole-cell patch-clamp recordings in slices from ChATtdTom mice (Fig. 5a).
In order to definitively ascertain the functional contribution of lymphotoxin (LT) expressed by B cells, we produced mice with the LTβ gene deleted from B cells (B-LTβ KO mice).
To ascertain the functional integrity of renal and hepatic tissues of Wistar rats fed with processed cocoa bean-based beverages and raw cocoa bean products-containing diets by using biochemical and histological methods.
To ascertain the functional role of this mutation, biochemical studies with the mutant enzyme are needed along with genetic exchange studies in P. falciparum parasites.
Future studies under controlled conditions (using head cameras [57] or gaze trackers [2]) should ascertain the functional nature of these scanning strategies (e.g., fixation vs. peering).
Future investigations should ascertain the functional role of enhanced NO signaling in protection against various types of muscle atrophy and elucidate the molecular mechanism(s) responsible for the fiber type-specific expression of iNos and antioxidant genes.
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