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The present work further ascertained previously reported haplogroups, and refined the phylogenetic tree of South Asia.
Basonuclin was likely an rRNA transcription regulator, but its relation to Pol I had not been ascertained previously.
Reproducibility and reliability of this procedure have been ascertained previously for both automatic segmentation and manual tracing [ 8, 27, 29].
The potential effect on allogeneic BM engraftment after nonmyeloablative conditioning which is of relevance for clinical BMT has not been ascertained previously.
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The presence of BRCA1 mutations was ascertained as previously reported [16], whereas sporadic cases were selected based on negative family history of cancer and age of onset >40 years.
W-H grade 0 or minimal encephalopathy was ascertained as previously described [ 28].
W-H grade 0 encephalopathy was ascertained as previously described [ 23].
The state of microglial activation was ascertained using previously published methods [ 17].
Probands (median age 31.4; range 17.6 56.3) were ascertained as previously described (8), many through psychiatric sources or referrals, ensuring a high rate of schizophrenia.
The second group included 43 patients with type 2 diabetes diagnosed at age ≥35 years for whom no insulin therapy was used for at least 2 years after diagnosis, ascertained as previously described (13).
Nineteen Finnish three-generation families (130 subjects; Table 1), of Caucasian origin and whose phenotypes were ascertained as previously described (Nopola-Hemmi et al. 2001), were genotyped (Kaminen et al. 2003; Anthoni et al. 2007).
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