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A smaller number of studies have been based on epidemiologically ascertained groups (Beitchman et al., 1989, 1990; Tomblin, Zhang, Buckwalter, & Catts, 2000; Whitehouse, Robinson, & Zubrick, 2011).
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A significant interaction term resulted in adjusted ordinal models run by group to ascertain group differences.
Experienced physicians may be able to ascertain group assignment based on their experience.
Nonparametric measures of association were used to ascertain group differences across categorical variables or where normality assumptions of continuous variables could not be strictly met.
To further confirm the genetic contribution of rs5848 to the development of FTLD, we focused our analyses on a homogeneous series of patients with a primary neuropathological diagnosis of FTLD-U with confirmed TDP-43-positive neuronal inclusions, derived from the MCJ brain bank and an age- and gender-matched control group ascertained at MCJ and MCS.
In an effort to identify a pathophysiological marker in TD, we ascertained a group of severely affected subjects.
To identify a pathophysiological marker, we ascertained a group of severely affected TD patients using the Distorted Tunes Test, an ecologically valid task with a longstanding history, and used electrophysiological methods to characterize the brain's responses to correct and incorrect melodic sequences.
Facilitators and the NeoKIP researchers jointly ascertained the group performance.
We first tested for differences between groups (Baltic coast, coastal lakes, inland no predators, inland predators) using a general linear mixed model (GLMM) using group as a fixed factor and population nested within group as a random factor to ascertain whether groups significantly differed in standard length and the number of dorsal spines.
A total of 687 CNVRs were found to overlap between the two groups (ascertained as CNVRs in both group) together with 98 and 407 CNVRs uniquely ascertained in Sus scrofa and Sus-ISEA group, respectively (Additional file 6: Table S4B and S4E).
Fisher's post hoc Least Significant Difference (LSD) t tests were used for all pairwise comparisons whenever the f ratio in ANCOVA models was significant (P ≤ 0.05), to ascertain which groups were different from each other.
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