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However, he noted that "certain issues can only be ascertained and reviewed after the event has taken place".
In the present study, all available karyotypic strings were retrospectively ascertained and reviewed, enabling cytogenetic subclassification and clinicogenetic analyses of a large, well-defined, representative and thus predominantly old AML population, and used to assess the impact on outcome of cytogenetic risk classification systems in this patient cohort.
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Whilst the exclusion of these sources of literature may result in our review reflecting less than the existing evidential base, it was beyond the scope of this study to systematically ascertain and review grey literature and dissertations.
End points were ascertained and confirmed after review of medical records.
Cases of fetal hydrocephalus unrelated to neural tube defects were ascertained from multiple sources and reviewed.
Vaccination service statistics (the EPI service time, the frequency of the vaccination service, number of attendance of the vaccination session) were collected from each immunization clinic and reviewed to ascertain the changes in performance of vaccination service.
All clinical data was ascertained after reviewing and collecting data from the patient's medical records.
All links advertised on the overview page were also accessed and reviewed to fully ascertain the degree of professional involvement in the app design.
Mortality and cause of death were ascertained by reviewing clinical charts and crosschecking with the Catalonian mortality register, as of December 31st , 2010
The above information was ascertained by reviewing the anesthesia pre-operative assessment note and the history and physical examination documented in each patient's EMR.
The infant vaccination status was ascertained by reviewing vaccination records in the Child Health Development Record or any other alternative documentary evidence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com