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Apoptosis studies were carried out to ascertain the mode of cell death.
The molecular docking study was carried out to ascertain the mode of action towards the molecular target DNA and enzymes.
The ligand-binding ability of this lectin, correlated with the insecticidal property, facilitated to ascertain the mode of action of the particular lectin on above mentioned insects physiology.
In the present study, we have attempted to ascertain the mode of binding of coumarin with calf thymus DNA (Ct-DNA) through various biophysical techniques.
Interaction of 1 and 3 with CT DNA was carried out by optical methods to ascertain the mode of binding, mechanism of action and their therapeutic potential.
In order to further ascertain the mode of RhB uptake onto the adsorbent used, leaching/desorption of RhB from DNC and CCDNc was investigated using deionized water, 0.1 M HCl and 0.1 M CH3COOH.
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A series of biophysical experiments were performed to ascertain the binding mode between ticlopidine and calf thymus DNA.
As such, trial participants and trial staff (eg, Research Nurses, Clinician Principal Investigators) should be engaged during development of trial decision aids to ascertain the best mode of delivery in the trial population.
For certain laminate architectures, several modes must be computed to ascertain the lowest buckling mode, and once identified, provides an excellent approximation for the mode computed using the Rayleigh Ritz method.
The molecular docking technique was also utilized to ascertain the mechanism and mode of action of diphenyltin analog 3. The in vitro antitumor activity of 3 was evaluated by SRB assay against a panel of human cancer cell lines which clearly revealed good cytotoxic activity against K-562 human leukemic cells with GI50 values <10 μg/ml.
Although the observed aggregation of affection status in the data points to familial association and is consistent with an inheritance basis, we had to evaluate all relevant possible genetic models to ascertain the most likely mode of inheritance.
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