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When intergenic loci are identified, it is important to ascertain the functional consequence of the variant on the neighboring genes.
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And though much more research is needed to ascertain the functional consequences of these brain changes, in some tests, heavy users demonstrated a reduced ability to solve complex problems on intelligence tests and showed signs of short-term memory loss.
We next compared the transcriptional competences of rH1-chromatin vs. chromatin to ascertain the functional consequences of H1 incorporation.
Future work will focus on ascertaining the functional consequence of cyclin D1 regulation by the BRCA1 BARD1 complex; in particular, the impact of BRCA1, mediated through regulation of cyclin D1, on the proliferation versus differentiation decision.
To ascertain the functional and mechanistic consequences of the expanded oligomer structures described above, standard holdase assays in which aggregation of a model client protein is monitored as a function of time in the absence and presence of sHSP were performed.
To ascertain the functional role of stress-induced CRF release onto LDTg cholinergic neurons, and the respective contribution of CRF-1 or CRF-2 receptor subtypes, we performed whole-cell patch-clamp recordings in slices from ChATtdTom mice (Fig. 5a).
Transgenic experiments may be necessary to ascertain the functional importance of this residue.
Fundamental parameters that ascertain the functional ability of spermatozoa are sperm count, motility, and sperm morphology [ 2].
Thus, the functional consequence of Nef on MHC-I and CD4 expression is different.
This study examines the functional consequence of evolutionary changes in the Endo16 promoter of sea urchins.
And while deterrence involves persuading others that you're a badass, the functional consequence of deterrence is peace.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com