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To ascertain markers that are informative to differentiate Pygmy populations, we computed two different estimates of the I n statistic.
In parallel, a single population FST (Weir and Cockerham, 1984) strategy was applied to ascertain markers that differentiate each population (Kersbergen, et al., 2009).
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For example, given the endangered status of many New World taxa, the existence of easy-to-ascertain markers (via a single PCR) to identify species-specific Alu insertions in tissues of unknown origin will be a boon to conservation biologists and to population geneticists.
The two candidates, BTD and GPX3, confirmed by this approach were next tested with immunoblot assay in a blinded set of breast cancer and control to ascertain the markers ability to differentiate the two groups.
In addition to the information on the prevalence of complications, it will ascertain whether markers of severe maternal morbidity can be incorporated into routine data collection systems, and provide a standardized evaluation of quality of care in a large number of health facilities in different geographical regions.
For example, one question that remains controversial is whether a population-specific or mixed-population reference sequence panel should be used for genome imputation, to ascertain untyped markers when attempting to fine-map admixed populations or populations without a precisely matching reference panel [ 69– 72].
Linkage was ascertained with markers close to the COL9A2 gene, which was analyzed for mutations by sequencing.
Traditional methods to ascertain ancestral informative markers usually require the prior knowledge of individual ancestry and have difficulty for admixed populations.
While in most cases it is not possible to ascertain whether overgo markers were solely responsible for contig builds or merges in the physical map, we have determined that at least 89 of the overgo markers shown in Figure 4 confirmed the in silico alignment of the BES to the corresponding pseudomolecule of O. sativa chromosome 1, providing robustness to the physical map.
An understanding of the relationship among these different populations and ascertaining ancestry informative markers (AIMs) that can discern East Asian substructure will undoubtedly facilitate accurate interpretation of such studies[5].
In these LGs an association analysis was performed to ascertain the microsatellite marker with the highest apparent effect on the trait, in order to test the possibility of using them for marker assisted selection.
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