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To ascertain function, classified genes were annotated with GO-SLIM terms by which initial, persistent, and latent gene groups were annotated with 398, 146, and 665 functional terms, respectively.
The JIA-associated clusters (same colour code in Figure 2B and C; listed in Additional file 3: Table S3A) within the MEN were mapped onto biological pathways using the Reactome Cytoscape plugin to ascertain function.
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To date, traditional phylogenomic studies concentrate on the search for orthology groups in gene family trees to infer the function of unknown proteins, yet the use of such phylogenies to ascertain the function of the encoded proteins is overlooked.
Once candidate genes are identified, functional validation is needed to ascertain the function of the candidate.
New genetic tools have been developed and we can now ascertain the function of individual genes.
The preferred symbol was submitted to NCBI AceView as well as extensive PubMed Boolian logic searches to ascertain the function of the gene in adipose tissue.
This is the first time that that this assay has been used to ascertain retinal function after cellular therapy in a retinal degenerate animal.
Technicians and engineers inspected all public access water sources to ascertain seasonality, function, and geospatial coordinates.
We were unable to ascertain pancreatic function status for 21 subjects.
A literature search was performed on the 130 genes in the list to ascertain their function.
Experimental validation is required to ascertain the function of this putative Ψ-dependent methyltransferase (work in progress).
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