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While the cross-sectional study design does not allow one to ascertain causative associations between PTSD factors and alcohol consumption and consequences, results generally align with the self-medication hypothesis, as PTSD factors reflecting internalizing were most strongly related to alcohol-related consequences.
Early broad-spectrum antimicrobial therapy with appropriate diagnostic studies to ascertain causative organisms is well established; there should be reassessment with the aim of using narrow-spectrum antibiotics to prevent the development of antimicrobial resistance, to reduce toxicity and to reduce costs [ 1].
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Since T2* values are influenced by a number of factors like field inhomogeneity, tissue oxygenation, blood flow and tissue distribution of paramagnetic substances like iron, a much more detailed study needs to be conducted to ascertain the causative factors behind this observation[32].
Additional studies are required to ascertain the causative variant, its functional significance and any possible counterbalancing selective pressures.
Importantly, to ascertain a causative role for AGE on myocardial inflammation future studies should be performed investigating the effect of sRAGE or AGE formation blockers.
That our study has been of cross-sectional design, unfortunately, does not enable us to ascertain the causative nature of co-relationships between variables.
Secondly, as diagnosis of screen detected CIN2/CIN3 peaks in the 20 29 year old age group in Australia, and infection occurs very shortly after sexual debut, we are prospectively typing HPV in CIN3 lesions diagnosed in women within this age group to ascertain the current causative HPV types in the post vaccine implementation period.
We do not have data on the presence of other bacterial or parasitic pathogens, thus we are therefore unable to ascertain which pathogen is the causative agent of the diarrhoeal episode.
In assessing the medical relevance of a CNV for a patient with a range of observed phenotypic abnormalities, it is essential to ascertain whether the CNV is causative for the disease and/or is merely incidental.
Ideally, adequate therapy must be started much before candidemia is ascertained, therefore much before the causative Candida species is identified and its susceptibility to antifungals is known.
Psychiatric disorders have been ascertained to be a major causative factor for SB [ 1- 3], and the treatment is expected to play an important role in reducing SB recurrence and preventing suicide [ 1].
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