Sentence examples for as yet poorly defined from inspiring English sources
Rnd3 can down-regulate RhoA.GTP levels by activating p190RhoGAP via an as yet poorly defined binding domain [3]; a complementary mechanism would be to inhibit RhoGEFs such as Syx (Figure 6).
The cellular and molecular composition of the human breast environment that maintains undifferentiated human primary epithelial cells is as yet poorly defined.
Limitations in coverage and sensitivity mean that a significant part of the chondrocyte ageing transcriptomic phenotype is as yet poorly defined.
While these observations point to a potential role for AM and its receptors in tumour angiogenesis, their role in human cancer is as yet poorly defined.
To approach the as yet poorly defined TSLP-induced signal transduction in dendritic cells, we established a cellular model system on the basis of the murine pro-B cell line Ba/F3.
It is therefore tempting to speculate that taxanes may induce these serum cytokine profiles either indirectly by their cytotoxic effect on tumour cells leading to secondary immune recognition of released tumour-derived antigens by tumour-infiltrating monocytes and B cells or by an as yet poorly defined direct effect on cells of the immune system or haematopoietic cells in the bone marrow.
The range of clinical services evaluated are in some ways misleading as some tools included only single indicators of complex, yet poorly defined packages of services rather than specific measures (e.g. 'family planning' as one indicator rather than a series of individual service or process indicators).
90 Further, it is a disease characterised by an yet poorly defined phenotype.
Genomic instability remains an important, yet poorly defined, mechanism by which tumors accelerate their own evolution and survival.
Type 1 diabetes (T1D) results from complex yet poorly defined interactions between environmental agents, the immune system, and genetic factors.
The major side of effect of 4-1BB antibodyantreatmenteatment, at least in mice, appears to be an as yet poorly mechanistically defined inflammatory liver toxicity [10].
