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The results presented raise important questions regarding the need of using standard methodologies in dynamic model construction as well as in using experimental data for model validation.
Therefore, without complete analysis of their targets and pathways (interactome), caution should be taken in defining the role of deregulated miRNAs in liver cancer, as well as in using miRNAs in cancer therapeutics.
While some surge staff were familiar with the activities involved in their new assignments, many were unfamiliar with communicable disease control and epidemiology functions and required Just-in-Time Training (JITT) in conducting case and contact investigations, as well as in using personal protective equipment, such as N95 respirators.
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Once the stability map is known, packaging can be designed to maintain the stability over the shelf life of the product as well as in-use stability in the hands of the patient.
Biofilm dosimetry was applicated in space experiments as well as in use in remote areas on Earth.
In case of overgrowth, the strong covering of vegetation can cause problems in hydroelectric power plants and leads to limitations in ship and boat traffic as well as in use for bathing and fishing activities.
We test our approach in silico using data obtained from stochastic simulations as well as in vivo using experimental data collected from synthetic circuits constructed in yeast.
The proposed model identification and tuning rules show applicability and robustness in experiments on a test rigs as well as in simulations using the OLGA simulator.
Our studies found that gemcitabine decreased replication of MuLV in cell culture as well as in vivo using the MAIDS model.
Effect modification was explored in stratified models as well as in models using multiplicative interaction terms.
Work was done both with constitutive Aph1BC knock-out mice, as well as in vitro using conditional single cell deletion.
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