Sentence examples for as well as cell cycle from inspiring English sources
These include effects on DNA repair, transcription, and DNA replication, as well as cell cycle arrest, apoptosis, and senescence.
Inversely, LINC00173 expression was negatively associated with gene sets involved in stemness and cancer, as well as cell cycle progression (Fig. 3h).
(B) Heatmap depicting correlations of top 50 miRNAs with tumor suppressor or oncogenes from PI3K and MAPK pathways as well as cell cycle pathway from RPPA data.
Western blot analyses as well as cell cycle and TUNEL assays by flow cytometry suggested that the two compounds inhibited the growth of cancer cells via similar mechanisms.
Notably, pathway analysis showed that mRNAs encoding for proteins involved in EMT, as well as cell cycle regulatory proteins (e.g., E2F targets) were significantly enriched among the downregulated mRNAs (Supplementary Fig. 3a, Supplementary Data 1).
In contrast, DCX, ASCL1 and OLIG2, genes normally expressed by more differentiated neuronal progeny as well as cell cycle regulators CDKN2A and NF1, were preferentially expressed in the less aggressive tumors expressing low levels of CD95 (Figure 1f).
The formation of these DNA adducts leads to inhibition of transcription and replication, as well as cell-cycle arrest [ 1].
In addition, CDKN1A also inhibits the activity of proliferating cell nuclear antigen and blocks DNA synthesis and repair as well as cell-cycle progression.
An analysis of function annotations of proteins with long N-terminal or internal disordered segments revealed enrichment for protein kinases and phosphoproteins and associations with regulatory and transcription functions, as well as cell-cycle processes (Tables S1F and S4B).
CellTiter 96 AQ one solution cell proliferation kit (Promega) converting a tetrazolium compound to formazan for cell-viability measurement and Apo-BrdU (Phoenix Flow Systems, San Diego, CA, USA) for apoptosis as well as cell-cycle analyses were carried out according to manufacturer's instructions.
