As we hypothesized, compared with controls, brain regions previously identified to be impaired in drug addiction showed abnormal functional connectivity to the DMN in drug addicts in the present study.
These infections may trigger JRA, as has been hypothesized previously [ 26].
Such variation might reflect differences in host specificity, infectivity and/or pathogenicity among individual nematodes within a population or, in some cases, might be indicative of speciation events, as has been hypothesized previously for human hookworms [ 21, 22].
No increased fatty acid esterification was measured in CDD mice by [C4] dilution, as hypothesized previously (36), although we cannot exclude that a coexisting intrahepatic fatty acid pool that is not successfully labeled exists in our tracer studies and contributes to triglyceride accrual.
This suggests that the defect in the muscle fibres is due to a defect in structural maintenance rather than an impairment of myogenesis, as was hypothesized previously.
As hypothesized previously, a twintron arrangement may serve as a safe pathway in intron type switching.
As hypothesized previously (Markou et al, 1998; Harrison et al, 2001; Markou and Kenny, 2002), elevations in brain reward thresholds associated with withdrawal from drugs of abuse may be homologous, or at least analogous, to the symptom of 'diminished interest or pleasure' (ie anhedonia) characterizing nondrug-induced depressions (American Psychiatric Association, 1994).
Inter-individual variability in this drug drug interaction could potentially be related to polymorphisms in the gene coding for PXR, as hypothesized previously for tacrolimus [ 37].
Moreover, treatment with combinations of chemotherapy and radiation (Forastiere et al, 2003; Vermorken et al, 2007) might be affected by FADD expression due to 11q13 amplification, as hypothesized previously (Gibcus et al, 2007b).
This GTP may then be used to activate RHEB (Ras homolog enriched in brain) and RRAG, which would lead to autophagy inhibition, as hypothesized previously.,, Involvement of GLUD in amino acid sensing may have its implications for the interpretation of some data on autophagy published in the past.
More generally, the high association of gene expression at the early developmental stage (e.g. juvenile leaf) with a target trait at a later development stage (e.g. in seeds) is due to allelic, cis-acting variation rather than being a read-out of a transcription network, as hypothesized previously for the association in maize hybrids of transcript abundance variation in leaves with grain yield.
