In order to re-analyze Straus et al. [ 1] as closely as possible, we duplicated their final sample size of 807 families with valid scores on all the variables in their analyses.
However, as we performed duplicate measurements for each sample, it was possible to divide the dataset into 2 identical biological datasets B1 and B2 (see Additional file 4).
The reliability of our assessment was good, as we used duplicate data extraction until data extraction had a high level of agreement between two independent readers.
We were interested in the alterations of relative proportion of AS in duplicated genes and singletons.
Therefore, the proportion of duplicated genes (summation of AS duplicates and no AS duplicates) increases as the identity criterion decreases.
In this section we extend the distance measure to include delete operations as well as duplicate and duplicate-invert operations.
These authors suggest, as we do, that a duplicated copy of the nucleus-encoded chloroplast rpl10 gene has functionally replaced the lost mitochondrial rpl10 gene independently in Arabidopsis and rice.
The statistical cut off at old young age was p<0.01 when adjusted for multiple testing (B>0), while at old age the cut off was much more stringent (p<1E-7, B>10) as we had 6 technical duplicates in each sample as compared to 2 technical duplicates at young age, artificially lowering the standard error.
You gotta feel good about that, but it's our responsibility now to duplicate that as we go forward". The Ducks play their best when the aggression is dialed up.
Sequencing ∼50 library plasmids from our library suggested very efficient randomization of the Prb binding face, as we did not observe any duplicate sequences in this region.
As we have now removed the duplicates from the database the numbers of cases reported in the original article and the numbers of "previous" cases reported here are not the same.
