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As NMR lends itself to absolute quantifications, NMR-based quantifications of high abundant metabolites will be used as validation method for mass spectrometry-based platforms.
For the PLS analysis the test set method was used as validation method.
We already expressed a preferences for the application of recombinant modified nucleosomes as validation method in chromatin biology in the original version of the manuscript.
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Accordingly, for IP-type applications, mass spectroscopy-based validation using IP with input materials similar to those used in actual experiments (Peach et al., 2012; Hattori et al., 2013; Marcon et al. 2015) and IP of semi-synthetic nucleosomes (Grzybowski et al., 2015) are better suited as validation methods.
However, there are few plant species present in the literature with specifications for assessing the quality of the originating raw materials as well as validation methods that can be used for quantification of chemical markers which is essential for guaranteeing the efficacy and safety of the derived products [ 1].
10-fold cross validation was used as the validation method, and performance measures were chosen as the mean squared error and the correlation coefficient.
While this modelling approach is useful as a validation method, NAM itself is also an important tool for investigation.
The objective of this study was to evaluate the efficacy and clinical performance of the UCD system and to compare it with bite-wing radiography by using direct visual inspection during restoration preparation as a validation method.
In this study, we also used the Taqman microRNA assay system as a validation method, which is a method most widely used.
In the MAQC project, the quantitative accuracy of several non-microarray devices was checked, then quantitative RT-PCR (Taqman system) was selected as a validation method of microarray data.
Using the micro-CT technique as the validation method, voids were present in all root fillings.
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