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As to methodological issues, lifetime prevalences are in general higher than 1-year prevalences, but the exact time frame of headache (1 year, 6 or 3 months, or no time frame stated) seems to be of less importance.
The discrepancies between the studies concerning significant association with particular forms of vessel involvement might be attributed to the differences in the clinical profile of patients involved in different studies as well as to methodological differences in clinical assessments.
As to methodological differences, Stöber et al.'s positive results with the Catastrophic Interview technique were based on within-subject comparisons showing that the (non-clinical) participants' thinking about topics that they worried about was less concrete than their thinking about non-worry topics.
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Simultaneous assessment of MSVs and CNs can be achieved by PCR, cloning and Sanger sequencing, however, these methods are labour and cost intensive as well as prone to methodological bias introduced by bacterial cloning.
Research objectives stated in the Abstract and Introduction sections were coded as relating to methodological issues, efficacy, or safety/toxicity, as were statements summarizing results and conclusions chosen for inclusion in the Abstract.
All hospitals with at least one missing value in any of the output or input variables were omitted from the analysis so as to ensure that the methodological requirements of DEA were met.
However, as these were measured in different subjects, these differences are likely due to variation in subjects as opposed to methodological inconsistencies.
Numerical results presented in the Results sections were classified as relating to methodological issues, efficacy, or safety/toxicity.
In particular, it sometimes can be difficult to ascertain whether observed trends – or the lack thereof – are biologically meaningful as opposed to methodological artifacts (Postma 2006; Hadfield et al. 2010).
Thus, the observed differences between the Rb and O-water studies (−2 ± 33%) may be attributable largely to physiological variability as opposed to methodological biases due to differences in location, time or sequence order of the Rb and O-water measurements.
Results from the study will add to methodological as well as content-specific discourses on human resources for maintaining high levels of autonomy and quality of life in old age, even in the face of multiple health burdens and morbidity.
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