Sentence examples for as the uncoupling of from inspiring English sources

Within this context cell senescence can be characterized as the uncoupling of the rate of cell cycle progression and cell growth mediated by mTOR.

Other effects of aspirin have also been reported, such as the uncoupling of oxidative phosphorylation in mitochondria and an influence on nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) dependent intracellular signaling pathways [ 6].

The information obtained here, and that from previous studies on hypogean fauna, shows the importance of factors such as the uncoupling of morphological and genetic evolution, the role of climatic change and regressive evolution as key processes in leading to subterranean biodiversity.

For the next three centuries, as Harrison observes, "the uncoupling of land from its natural role as the source of revenue for the state continued apace".

However, during cerebrovascular pathologies such as cerebral ischemia, the uncoupling of neurovascular and gliovascular units can result in several phenotypical changes in brain endothelium.

The energy generated along the electron gradient of the OXPHOS chain may be converted in usable energy to the cell, in the form of ATP, or released as heat by the uncoupling of the OXPHOS, which is, for example, important for the thermogenesis of organisms that inhabit cold environments (Cannon and Nedergaard 2004).

Our findings show that unlike the results reported for S. cerevisiae, Set1 in S. pombe not only exerts more regulatory influence over the transcriptome, but also mediates its repressive function largely independently of the other Set1C subunits and H3K4 methylation probably, as a consequence of the uncoupling of Set1 protein stability from H3K4me levels (Mikheyeva et al., 2014).

Secondly, hypoxia induces production of the hypoxia inducible factor, which also promotes the uncoupling of NOS [ 81– 83] as well as the activation of arginase-2 [ 84].

The advantage of nitrate as a N source is the uncoupling of N supply and demand, while ammonium causes toxicity in cells which necessitates rapid assimilation and is limited by the carbon supply to roots [37].

The Davidge laboratory have shown that an increased arginase expression in pre-eclampsia can induce the uncoupling of NOS as a source of superoxide in the maternal vasculature in pre-eclampsia, and suggested that L-arg supplementation in the face of oxidative stress could lead to a further increase in peroxynitrite (Sankaralingam et al., 2010).

Matched annotations were used to estimate the uncoupling of functional information as the proportion of annotations overrepresented in the translatome but not in the transcriptome readings and vice versa.