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The phrase "as the substance" is correct and usable in written English.
It can be used when discussing the essential nature or core aspect of something in a specific context.
Example: "The report focused on the findings, but as the substance of the discussion, we must consider the implications of these results."
Alternatives: "in essence" or "at its core".
Exact(60)
Would Brenton get "slime" as the substance an oyster throws around invasive grit?
This is what Senator Burr saw as the substance at stake: Price's commitment to dismantling Obamacare.
The setting of Mr. Chalabi's message was almost as striking as the substance.
No doubt Clinton's style of leadership contributed to this impression as much as the substance did.
The Chicago Tribune first identified that as the substance in question.
These days plastic is displacing gold as the substance with which Indians most associate money.
It was the manner of Ashcroft's action, as much as the substance, that offended old-timers at the Justice Department.
Ultimately, it was not the tone so much as the substance of Dean's message that turned off his erstwhile supporters.
The manner in which the Administration reversed itself had been as remarkable as the substance of the reversal.
America's separation of powers may explain the odd presidential travel plans as well as the substance of the offer.
The room was crowded with doctors, nurses and medical students who were silent as the substance was injected.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com