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This is a problem of major biological importance, as the reshaping of DNA methylation patterns throughout the genome is connected to a variety of human diseases, including (but not limited to) imprinting syndromes, autoimmune diseases, and cancer.
In general, evolutionary plasticity induced by transposon activity can be regarded as the reshaping of genomes by rearranging chromosomes and increasing the frequency of both structural gene and regulatory sequence mutations (Schmidt et al. 2012; see Shapiro 2010 for a discussion).
This study recognizes the variety of worlds that have been opened up to NASA and its partners by small, relatively inexpensive, missions of the Discovery class, as well as the reshaping of our ideas about life in the solar system that have been occasioned by the Galileo spacecraft's discovery that an ocean under the ice on Jupiter's moon Europa might, indeed, exist.
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Over the last 20 years Martin has helped launch the careers of Britney Spears, Robyn, N'Sync, Katy Perry and the Backstreet Boys, as well as reshaping the fortunes of the likes of Pink, the Weeknd, Ariana Grande, Kelly Clarkson and Taylor Swift.
As the reshaped powder dries, it will form a solid cake.
In another dizzying day that will long be remembered as part of the reshaping of college sports, two universities with brand-name football programs announced they were leaving their conferences.
This sets the scene for February, she said: "At the most basic level, February's two elections are important if they end up confirming that competitive electoral politics – within the confines of the Islamic Republic – have become critical in deciding the policy direction of the country as well as reshaping its balance of power.
"We recognise that our employees are making real sacrifices in accepting the current changes, so we want to work with unions on how they can benefit as the council reshapes the way it operates in the years ahead.
Joan Littlewood (1914-2002) was a dynamic genius, whose Theatre Workshop, resident at the Theatre Royal, Stratford East, did as much to reshape the landscape in the 1950s and 60s as the Royal Court.
As the industry reshapes itself amid declining competitive pressures, some airlines have the opportunity to rebrand parts of themselves in a higher-premium niche, said Paul D'Alessandro, the customer service expert at Pricewaterhouse.
Yet as the academy reshapes its mission and campus, its flowering relationship with the art market is stirring unease among those who feel that students should be shielded from commercial pressures.
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