The phrase "as the main problem with" is correct and usable in written English.
It can be used when discussing a specific issue or challenge that is considered the most significant among others.
Example: "The report highlights communication breakdowns as the main problem with the project’s progress."
Alternatives: "as the primary issue with" or "as the key challenge with".
However, such an assumption is impractical, as the main problem with most OR protocols is duplicate transmissions due to failure in acknowledgment propagation.
As the main problem with complex systems is ensuring that the system continues to run safely, there has been significant research devoted to the maintenance of complex systems to extend the life of normal operations.
Severe shortage of medicines was reported as the main problem with drug distribution in this area.
Upon later examination, inclusion criteria were non- traumatic neck pain as the main problem with a score of 3 or more on numerical rating scale (NRS; 0 10), where 0 represent no pain and 10 worst imaginable pain, at the day of testing and the current neck pain episode lasting >2 weeks.
You mention price as being the main problem with the MarthaStewart.com site, but I've had numerous technical problems.
As already commented, the main problem with wireless underground communication is the very high signal attenuation caused by the soil [1, 4, 5, 7].
As Mr. Greenspan says, "The main problem with that explanation is that there is no actual evidence of a global savings glut".
The main problem with this idea, as far as I can see, is that it doesn't stop with education.
In other words, the nearby relay nodes may act as auxiliary receivers/transmitters for the original transmitter/receiver. But, again the main problem with cooperative terminals as indicated by Li and Xia [5, 6] is the asynchronous nature of transmission which forces the traditionally designed space-time codes to lose their diversity and coding gain when used over distributed cooperative networks.
Despite wonderful highlights such as the scene with the gooseberry, the main problem with Mr Turner is that it has no real narrative.
As the producers are starting to realise, the main problem with adapting the whole Narnia series is that most casual audiences only really care about The Lion, the Witch and the Wardrobe.
