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For the second model, we randomly selected 33 genes as the initial expression traits used to determine the subnetworks and repeated the entire analysis.
We also performed a more stringent estimation of the null distribution by randomly selecting 33 genes as the initial expression traits and replicating the analysis 1,000 times.
We obtained SNP summary statistics through the Database of Genotypes and Phenotypes (dbGaP; dbGaP Study Accession: phs000091.v2.p1) and performed the same permutation analysis by randomly selecting 33 genes as the initial expression traits.
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The heterologously expressed COS BTPC mutants were subject to the same problems of irreversible aggregation, inactivation and precipitation as was observed during the initial expression and purification of recombinant wild-type RcPPC4 [ 24].
As shown in figure 8, the initial expression domain of toy at the cellular blastoderm stage is cooperatively regulated by the three maternal patterning systems (the anterior, terminal, and dorsoventral systems) cooperatively with the zygotically active gap genes.
Factors that drive the initial expression of IL-4 (as the major Th2-defining cytokine) in human naive CD4+ T cells include costimulation via CD28 in concerted action with TCR engagement [ 22].
Indeed, it is the initial expression of functional properties.
This coincides with the initial expression of AQP4.
Due to research budget constraints, we selected only a single time point as the initial global expression screening.
JKC oversaw all genomics aspects of the analysis, identified appropriate annotation methods for pathway and completeness analysis as well as performing initial expression analysis, submitted microarray data, and contributing substantially to the manuscript.
More mature osteoprogenitor population was found in the first culture, as the initial stock had higher BSP expression level, ALP activity increased sooner, and mineralization started earlier than in the second culture.
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