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Based on the thiophilic property of Hg2+, using C = S structural motif as the core segment, our group have designed and synthesized three novel probes containing cinnamyl aldehyde with different substituents, exhibiting high selectivity and excellent sensitivity.
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As viewed in the standard orientation, all USS consensuses have an AT-rich motif just 3' of the core (segment 2; positions 22 27 as numbered in Fig. 4B), with the first bases usually 'A's and the final 3 or 4 bases 'T's.
The core segment of the oral healthcare sector comprises goods as defined in the Health Expenditure Account.
The docking procedure consisted of rigid body docking of terminal core fragments, central loop closure, constrained all-atom refinement of the core segment, and extension of the core segment.
The mismatched and GU pair scores within the core segment (at positions 2 13) were doubled.
The resulting trimmed sequence is defined as the "cyclohexadienyl-substrate core segment".
The hydrophobic domains of CA form the inner core segment and act as a potential drug-incorporation site in the PM, which facilitates transportation of the drug cargo across the cell membrane.
At pH 5.8 and 25 °C, the block copolymer self-assembled into spherical core shell micelles with hydrophobic PtBA segments as the core, hydrophilic PAA/PNIPAM segments as the mixed shell.
Above the lower critical solution temperature (LCST) of PNIPAM segment, the polymer can self-assemble into nano-sized assemblies, where PNIPAM segments serve as the core and PEG segments are organized as the corona.
The exact core segment and bilateral tolerant segments of HREs were obtained and formulated as a novel matrix for motif searching and evaluation.
To determine the relative declinations for as long a continuous interval as possible, for each core segment, we confirmed whether its end surface could be connected to the next core segment and carefully checked the connection between the two segments without any horizontal rotation to ensure the continuity of the core.
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