The phrase "as the ameloblasts progress" is correct and usable in written English.
It can be used in contexts related to biology, particularly in discussions about tooth development and the role of ameloblasts in enamel formation.
Example: "As the ameloblasts progress, they secrete enamel matrix proteins that contribute to the formation of the tooth enamel."
Alternatives: "as the ameloblasts advance" or "as the ameloblasts develop".
In later stages of teeth development, this area extended as the ameloblast differentiation progressed and proliferation decreased in teeth mesenchyme (Fig. 6d).
Rodent ameloblasts progress from the secretory stage to the final maturation stage in a matter of weeks whereas enamel development in humans may take years.
Therefore, ameloblasts progress through defined developmental stages that require intercellular contact and communication.
During the pre-secretory stage, ameloblasts are separated from the adjacent neural crest cell-derived odontoblasts by a basement membrane which is subsequently removed as the ameloblasts enter their secretory phase.
As the ameloblasts retreat away from the dentine, they lay down an extracellular matrix within which the hydroxyapatite crystals begin to form.
As the ameloblasts entered the maturation stage, during which rapid crystal growth appears and mineral content dramatically increases, they shortened and the proteins were removed from the enamel ECM as evidenced by the loss of staining (Fig. 4C).
As the ameloblasts enter their maturation phase, the organic matrix is degraded completely to allow secondary growth of the hydroxyapatite crystals which ultimately occlude the spaces previously occupied by the enamel extracellular matrix proteins.
(4) During the secretory stage of amelogenesis, long thin ribbons of enamel mineral crystals are formed almost immediately as the ameloblast lays down enamel matrix proteins, suggesting that enamel mineralization does not take place within a preformed matrix.
This may be because the continuously erupting mouse incisor ameloblast progresses from the secretory stage to the final maturation stage in a matter of weeks, whereas this progression occurs over several years for human teeth.
Following maturation, the ameloblasts become cuboidal and progress forwards until they reach the gingival margin where the tooth erupts from the mandible (14, 15).
