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In resource-limited settings, if it is possible to measure baseline viral load, an early measure of viral load on treatment (for example at four to six weeks) would be arguably more valuable than at the six month visit as suggested, for example, in South African guidelines [ 29].

The transition probabilities of a Markov chain of arbitrary order can be estimated from the observed data using the maximum likelihood strategy, as suggested for example in[21, 22].

To sum up, the pattern of brain activation observed in musicians compared to nonmusicians reflects a constant interaction between episodic and semantic memory during the familiarity task as suggested, for example, by the MNESIS model [43].

Global metabolomic profiling may be more amenable than transcriptomic or proteomic profiling to high-throughput screening, as suggested for example by studies showing that the main yeast metabolome consists of fewer than 600 low-molecular-weight compounds.

Which of the 'shadow enhancers' associates with a target promoter at a given point of time may be down to random chance – as suggested, for example by the diversity of DNA looping interactions observed across single cells 41.

Furthermore, respiratory mechanics widely differs between humans and rodents, as suggested, for example, by the different physiological respiratory rates that are relatively higher in the latter species and may, therefore, influence gas transport and exchange [ 6].

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Putatively, the receptor activity could be regulated at the expression level as the constitutive activity is proportional to this, as suggested for, for example, the orphan 7TM receptor EBI2 (Rosenkilde et al., 2006).

Periodically it is reported that infarction of certain small regions reliably result in a specific and lasting aphasic deficit, but such reports may attract further studies suggesting that the anatomical-behavioural association is not as strong as originally suggested (for example, see Dronkers, 1996, and the subsequent paper by Hillis et al., 2004).

Possibly, free-standing MT domains may be employed by some algal trans-AT PKSs, as has been suggested, for example, in the case of oxazolomycin biosynthesis in Streptomyces [ 32].

Some Roman aristocratic families must have survived among the Lombards, as is suggested, for example, by the name of a royal protégé and founder of a monastery in Pavia in 714: Senator, son of Albinus.

The source of such seed perturbation is now widely recognized to be upward propagating gravity waves originating from tropospheric convective activity as past studies have suggested (for example, Röttger 1973).

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